f635ced9abfe2764481d63b57d99b46a06778489
HIST1H1D.md
| ... | ... | @@ -21,24 +21,18 @@ Mutations are often found in the globular domain of the protein, which is critic |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | -|Entity|source |frequency (%)| |
|
| 25 | -|:------:|:---------------------:|:-------------:| |
|
| 26 | -|BL |GAMBL genomes+capture|3.23 | |
|
| 27 | -|BL |Thomas cohort |4.70 | |
|
| 28 | -|BL |Panea cohort |4.00 | |
|
| 29 | -|DLBCL |GAMBL genomes |6.12 | |
|
| 30 | -|DLBCL |Schmitz cohort |5.74 | |
|
| 31 | -|DLBCL |Reddy cohort |6.11 | |
|
| 32 | -|DLBCL |Chapuy cohort |7.69 | |
|
| 33 | -|FL |GAMBL genomes |3.23 | |
|
| 24 | +### DLBCL |
|
| 25 | +[[include:DLBCL_HIST1H1D.md]] |
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| 26 | + |
|
| 27 | +### BL |
|
| 28 | +[[include:BL_HIST1H1D.md]] |
|
| 29 | + |
|
| 30 | +### FL |
|
| 31 | +[[include:FL_HIST1H1D.md]] |
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| 34 | 32 | |
| 35 | 33 | ## Mutation pattern and selective pressure estimates |
| 36 | 34 | |
| 37 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 38 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 39 | -|BL |No |No |8.064 |0 | |
|
| 40 | -|DLBCL |No |No |2.458 |0 | |
|
| 41 | -|FL |No |No |0.857 |0 | |
|
| 35 | +[[include:dnds_HIST1H1D.md]] |
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| 42 | 36 | |
| 43 | 37 | |
| 44 | 38 |