STAT6.md
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## Overview
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The STAT6 gene, which encodes a transcription factor involved in the JAK-STAT signaling pathway, plays a significant role in the pathogenesis of various lymphomas, including diffuse large B-cell lymphoma (DLBCL). Below is a summary of the common mutations in the STAT6 gene identified in DLBCL. Mutations in the DNA binding domain of STAT6 are common in PMBCL and more rare in DLBCL.
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-## History
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-```mermaid
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-%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
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-timeline
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- title Publication timing
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- 2009-08-06 : Ritz : PMBL
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- 2015-01-22 : Yildiz : DLBCL
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-2017-05-01 : Albuquerque : DLBCL
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-2017-10-10 : Reddy : DLBCL
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-2018-04-12 : Schmitz : DLBCL
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-2018-05-01 : Chapuy : DLBCL
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-2018-10-01 : Arthur : DLBCL
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-2021-05-05 : Hubschmann : DLBCL
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-```
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## Relevance tier by entity
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<!-- FL: yildizActivatingSTAT6Mutations2015c -->
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<!-- DLBCL: yildizActivatingSTAT6Mutations2015c -->
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+[[include:mermaid_STAT6.md]]
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+
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## References
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mermaid_STAT6.md
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+## History
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+```mermaid
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+%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
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+timeline
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+ title Publication timing
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+ 2009-08-06 : Ritz : PMBL
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+ 2015-01-22 : Yildiz : DLBCL
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+2017-05-01 : Albuquerque : DLBCL
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+2017-10-10 : Reddy : DLBCL
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+2018-04-12 : Schmitz : DLBCL
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+2018-05-01 : Chapuy : DLBCL
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+2018-10-01 : Arthur : DLBCL
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+2021-05-05 : Hubschmann : DLBCL
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+```