Gene Status First BL study Other lists
ARID1A BL Tier 1 Love et al DLBCL, FL, PMBL, MZL
BACH2 BL Tier 1 Grande et al
BCL6 BL Tier 1 Love et al DLBCL, FL
BCL7A BL Tier 1 Grande et al DLBCL, FL, PMBL, MZL
BMP7 BL Tier 1 Panea et al
CCND3 BL Tier 1 Richter et al DLBCL, FL, PMBL, MZL
CHD8 BL Tier 1 Grande et al PMBL
CREBBP BL Tier 1 Love et al DLBCL, FL, PMBL, MZL
DDX3X BL Tier 1 Schmitz et al DLBCL, FL, PMBL
EZH2 BL Tier 1 Love et al DLBCL, FL, PMBL, MZL
FBXO11 BL Tier 1 Richter et al DLBCL, MZL
FOXO1 BL Tier 1 Schmitz et al DLBCL, FL, PMBL, MZL
GNA13 BL Tier 1 Schmitz et al DLBCL, FL, PMBL
GNAI2 BL Tier 1 Grande et al DLBCL, FL
HIST1H1E BL Tier 1 Grande et al DLBCL, FL, PMBL
HNRNPU BL Tier 1 Panea et al DLBCL
ID3 BL Tier 1 Richter et al DLBCL, MZL
IGLL5 BL Tier 1 Panea et al DLBCL, FL, PMBL
KMT2D BL Tier 1 Grande et al DLBCL, FL, PMBL, MCL, MZL
MYC BL Tier 1 Johnston et al DLBCL, FL, PMBL, MZL
P2RY8 BL Tier 1 Muppidi et al DLBCL, FL, PMBL
PCBP1 BL Tier 1 Schmitz et al PMBL
PHF6 BL Tier 1 Thomas et al DLBCL
PTEN BL Tier 1 Love et al DLBCL
RFX7 BL Tier 1 Grande et al DLBCL
RHOA BL Tier 1 Richter et al DLBCL, FL, PMBL
SIN3A BL Tier 1 Grande et al DLBCL, PMBL, MZL
SMARCA4 BL Tier 1 Richter et al DLBCL, FL, PMBL, MCL
TCF3 BL Tier 1 Schmitz et al PMBL
TCL1A BL Tier 1 Grande et al DLBCL
TFAP4 BL Tier 1 Grande et al
TP53 BL Tier 1 Wilda et al DLBCL, FL, PMBL, MCL, MZL
USP7 BL Tier 1 Grande et al DLBCL
WNK1 BL Tier 1 Thomas et al DLBCL, MZL

Citing

If you use the information or data from this site, please cite

Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.

Disclaimer

The content in these pages has been populated, in part, by an automated process. Although we have scrutinized every page to ensure accuracy, errors will inevitably exist. If you find an error please report it as an issue and we will address it.

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

You are free to:

Share — copy and redistribute the material in any medium or format for any purpose, even commercially.

Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms.