Morin et al. (2011)

Summary of novel genes

Entity Tier 1 genes Tier 2 genes Tier 3 genes
DLBCL 28 4 0
FL 21 4 0
--- config: sankey: showValues: true linkColor: target width: 600 height: 300 nodeAlignment: right prefix: '(' suffix: ' genes)' --- sankey-beta This study, New Tier 1, 28 New Tier 1, DLBCL Tier 1, 28 This study, New Tier 2, 4 New Tier 2, DLBCL Tier 2, 4 This study, New Tier 3, 0 New Tier 3, DLBCL Tier 3, 0 All other DLBCL studies, DLBCL Tier 1, 101 All other DLBCL studies, DLBCL Tier 2, 174 All other DLBCL studies, DLBCL Tier 3, 385

Novel genes reported in this study

Tier 1

New gene DLBCL tier FL tier
B2M 1 1
BCL10 1 2
BCL2 1 1
BCL6 1 1
BCL7A 1 1
BTG1 1 1
BTG2 1 1
CARD11 1 1
CCND3 1 1
CD58 1
CD70 1 2
CD79B 1 2
ETS1 1
FOXO1 1 1
GNA13 1 1
HIST1H1C 1 1
IRF4 1 1
IRF8 1 1
KLHL6 1 1
KMT2D 1 1
MEF2B 1 1
S1PR2 1 1
SGK1 1 1
SOCS1 1 1
TMEM30A 1 2
TNFRSF14 1 1
TP53 1 1
ZFP36L1 1

Tier 2

New gene DLBCL tier FL tier
CD274 2
CIITA 2
FAT2 2
RAPGEF1 2

Details

Morin, Ryan D., Maria Mendez-Lago, Andrew J. Mungall, Rodrigo Goya, Karen L. Mungall, Richard D. Corbett, Nathalie A. Johnson, et al. 2011. “Frequent Mutation of Histone-Modifying Genes in Non-Hodgkin Lymphoma.” Nature 476 (7360): 298–303. https://doi.org/10.1038/nature10351.

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