Schmitz et al. (2012)
Summary of novel genes
| Entity | Tier 1 genes | Tier 2 genes |
|---|---|---|
| DLBCL | 2 | 3 |
| BL | 4 | 16 |
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This study, New Tier 1, 4
New Tier 1, BL Tier 1, 4
This study, New Tier 2, 16
New Tier 2, BL Tier 2, 16
All other BL studies, BL Tier 1, 25
All other BL studies, BL Tier 2, 141
Novel genes reported in this study
Tier 1
| New gene | DLBCL tier | BL tier |
|---|---|---|
| DDX3X | 1 | 1 |
| FOXO1 | 1 | 1 |
| ID3 | 2 | 1 |
| TCF3 | 1 |
Tier 2
| New gene | DLBCL tier | BL tier |
|---|---|---|
| C16orf48 | 2 | |
| DHCR7 | 2 | |
| ELP2 | 2 | |
| EXOSC6 | 2 | |
| FLYWCH1 | 2 | |
| GTSE1 | 2 | |
| KANK2 | 2 | |
| MKI67 | 2 | |
| MYO18A | 2 | |
| NCOR2 | 2 | 2 |
| PCBP1 | 2 | 2 |
| PDCD11 | 2 | |
| TOP2A | 2 | |
| WDR90 | 2 | |
| WHAMM | 2 | |
| YY1AP1 | 2 |
Details
Schmitz, Roland, Ryan M. Young, Michele Ceribelli, Sameer Jhavar,
Wenming Xiao, Meili Zhang, George Wright, et al. 2012. “Burkitt
Lymphoma Pathogenesis and Therapeutic Targets from Structural and
Functional Genomics.” Nature 490 (7418): 116–20. https://doi.org/10.1038/nature11378.