Summary of novel genes
| Entity | Tier 1 genes | Tier 2 genes | Tier 3 genes |
|---|---|---|---|
| PMBL | 1 | 0 | 0 |
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This study, New Tier 1, 1
New Tier 1, PMBL Tier 1, 1
This study, New Tier 2, 0
New Tier 2, PMBL Tier 2, 0
This study, New Tier 3, 0
New Tier 3, PMBL Tier 3, 0
All other PMBL studies, PMBL Tier 1, 45
All other PMBL studies, PMBL Tier 2, 112
All other PMBL studies, PMBL Tier 3, 0
Novel genes reported in this study
Tier 1
| New gene | PMBL tier |
|---|---|
| IL4R | 1 |
Details
Viganò, Elena, Jay Gunawardana, Anja Mottok, Tessa Van Tol, Katina Mak,
Fong Chun Chan, Lauren Chong, et al. 2018. “Somatic
Il4r Mutations in Primary Mediastinal Large B-cell Lymphoma Lead to Constitutive
JAK-STAT Signaling Activation.” Blood 131
(18): 2036–46. https://doi.org/10.1182/blood-2017-09-808907.


