BRAF Hotspots
| Chromosome | Coordinate (hg19) | DLBCL | FL | BL | HGVSp |
|---|---|---|---|---|---|
| 7 | 140453153,140453154,140453155 | 10 | 2 | 3 | D594G |
| 7 | 140453153,140453154,140453155 | 10 | 2 | 3 | D594N |
| 7 | 140453153,140453154,140453155 | 10 | 2 | 3 | D594A |
| 7 | 140453153,140453154,140453155 | 10 | 2 | 3 | D594E |
| 7 | 140481402,140481403 | 7 | 2 | 1 | G469A |
| 7 | 140481402,140481403 | 7 | 2 | 1 | G469E |
| 7 | 140481402,140481403 | 7 | 2 | 1 | G469R |
| 7 | 140481402,140481403 | 7 | 2 | 1 | G469V |
| 7 | 140453132,140453134 | 6 | 1 | 0 | K601E |
| 7 | 140453132,140453134 | 6 | 1 | 0 | K601N |
| 7 | 140453136 | 4 | 2 | 0 | V600E |
| 7 | 140453145 | 4 | 0 | 1 | L597R |
| 7 | 140453145 | 4 | 0 | 1 | L597Q |
| 7 | 140453150 | 2 | 0 | 1 | F595L |
| 7 | 140481417 | 1 | 0 | 1 | G464V |
| 7 | 140477806 | 0 | 0 | 1 | E501A |
| nan | nan | 1 | 0 | 0 | T599dup |
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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