DTX1 Hotspots
| Chromosome | Coordinate (hg19) | DLBCL | FL | BL | HGVSp |
|---|---|---|---|---|---|
| 12 | 113496211,113496212,113496213,113496210 | 11 | 2 | 0 | Y72Tfs*74 |
| 12 | 113496211,113496212,113496213,113496210 | 11 | 2 | 0 | Y72C |
| 12 | 113496211,113496212,113496213,113496210 | 11 | 2 | 0 | Y72D |
| 12 | 113496211,113496212,113496213,113496210 | 11 | 2 | 0 | Y72H |
| 12 | 113496211,113496212,113496213,113496210 | 11 | 2 | 0 | Y72N |
| 12 | 113496211,113496212,113496213,113496210 | 11 | 2 | 0 | Y72* |
| 12 | 113496211,113496212,113496213,113496210 | 11 | 2 | 0 | Y72S |
| 12 | 113496202,113496203 | 10 | 2 | 0 | L69F |
| 12 | 113496202,113496203 | 10 | 2 | 0 | L69V |
| 12 | 113496130,113496131,113496132 | 12 | 0 | 0 | C45* |
| 12 | 113496130,113496131,113496132 | 12 | 0 | 0 | C45W |
| 12 | 113496130,113496131,113496132 | 12 | 0 | 0 | C45R |
| 12 | 113496202,113496203 | 10 | 2 | 0 | L69P |
| 12 | 113496130,113496131,113496132 | 12 | 0 | 0 | C45F |
| 12 | 113496130,113496131,113496132 | 12 | 0 | 0 | C45S |
| 12 | 113496130,113496131,113496132 | 12 | 0 | 0 | C45Sfs*4 |
| 12 | 113496130,113496131,113496132 | 12 | 0 | 0 | C45Y |
| 12 | 113496096 | 10 | 1 | 0 | E33D |
| 12 | 113496087,113496085 | 9 | 2 | 0 | W30* |
| 12 | 113496087,113496085 | 9 | 2 | 0 | W30C |
| 12 | 113496087,113496085 | 9 | 2 | 0 | W30G |
| 12 | 113496115,113496116,113496117 | 6 | 2 | 1 | Y40C |
| 12 | 113496115,113496116,113496117 | 6 | 2 | 1 | Y40N |
| 12 | 113496115,113496116,113496117 | 6 | 2 | 1 | Y40* |
| 12 | 113496115,113496116,113496117 | 6 | 2 | 1 | Y40H |
| 12 | 113496115,113496116,113496117 | 6 | 2 | 1 | Y40S |
| 12 | 113496159 | 6 | 0 | 2 | E54D |
| 12 | 113496238,113496239,113496240 | 5 | 3 | 0 | Q81H |
| 12 | 113496238,113496239,113496240 | 5 | 3 | 0 | Q81* |
| 12 | 113496238,113496239,113496240 | 5 | 3 | 0 | Q81E |
| 12 | 113496238,113496239,113496240 | 5 | 3 | 0 | Q81L |
| 12 | 113496238,113496239,113496240 | 5 | 3 | 0 | Q81R |
| 12 | 113496173 | 4 | 1 | 2 | S59F |
| 12 | 113496082,113496083 | 5 | 2 | 0 | E29G |
| 12 | 113496082,113496083 | 5 | 2 | 0 | E29K |
| 12 | 113496169,113496170 | 6 | 1 | 0 | G58D |
| 12 | 113496241,113496242,113496243 | 4 | 3 | 0 | F82L |
| 12 | 113496241,113496242,113496243 | 4 | 3 | 0 | F82S |
| 12 | 113496169,113496170 | 6 | 1 | 0 | G58V |
| 12 | 113496139,113496140,113496141 | 5 | 1 | 1 | I48S |
| 12 | 113496173 | 4 | 1 | 2 | S59Y |
| 12 | 113496082,113496083 | 5 | 2 | 0 | E29V |
| 12 | 113496241,113496242,113496243 | 4 | 3 | 0 | F82C |
| 12 | 113496241,113496242,113496243 | 4 | 3 | 0 | F82I |
| 12 | 113496241,113496242,113496243 | 4 | 3 | 0 | F82Y |
| 12 | 113496169,113496170 | 6 | 1 | 0 | G58A |
| 12 | 113496169,113496170 | 6 | 1 | 0 | G58R |
| 12 | 113496139,113496140,113496141 | 5 | 1 | 1 | I48F |
| 12 | 113496139,113496140,113496141 | 5 | 1 | 1 | I48L |
| 12 | 113496139,113496140,113496141 | 5 | 1 | 1 | I48M |
| 12 | 113496139,113496140,113496141 | 5 | 1 | 1 | I48N |
| 12 | 113496139,113496140,113496141 | 5 | 1 | 1 | I48V |
| 12 | 113496173 | 4 | 1 | 2 | S59L |
| 12 | 113496256,113515229 | 5 | 1 | 0 | G87S |
| 12 | 113496155,113496156 | 5 | 0 | 1 | K53N |
| 12 | 113496155,113496156 | 5 | 0 | 1 | K53M |
| 12 | 113496088,113496089 | 5 | 0 | 1 | L31Q |
| 12 | 113496088,113496089 | 5 | 0 | 1 | L31V |
| 12 | 113496256,113515229 | 5 | 1 | 0 | G87R |
| 12 | 113496256,113515229 | 5 | 1 | 0 | G87V |
| 12 | 113496155,113496156 | 5 | 0 | 1 | K53R |
| 12 | 113496088,113496089 | 5 | 0 | 1 | L31P |
| 12 | 113496088,113496089 | 5 | 0 | 1 | L31Pfs*14 |
| 12 | 113496201 | 4 | 0 | 1 | Q68H |
| 12 | 113496133,113496135 | 4 | 1 | 0 | H46Q |
| 12 | 113496163,113496164 | 5 | 0 | 0 | A56G |
| 12 | 113496163,113496164 | 5 | 0 | 0 | A56S |
| 12 | 113496163,113496164 | 5 | 0 | 0 | A56V |
| 12 | 113496133,113496135 | 4 | 1 | 0 | H46N |
| 12 | 113496133,113496135 | 4 | 1 | 0 | H46Y |
| 12 | 113496144 | 4 | 0 | 0 | E49D |
| 12 | 113496176,113496175 | 2 | 1 | 1 | V60E |
| 12 | 113496144 | 4 | 0 | 0 | E49Dfs*90 |
| 12 | 113496176,113496175 | 2 | 1 | 1 | V60G |
| 12 | 113496176,113496175 | 2 | 1 | 1 | V60M |
| 12 | 113496233,113496234 | 3 | 0 | 0 | M79I |
| 12 | 113496208 | 3 | 0 | 0 | P71S |
| 12 | 113496076 | 3 | 0 | 0 | V27L |
| 12 | 113496191 | 2 | 1 | 0 | V65A |
| 12 | 113496205,113496206 | 2 | 0 | 1 | V70L |
| 12 | 113496197,113496196 | 3 | 0 | 0 | A67G |
| 12 | 113496197,113496196 | 3 | 0 | 0 | A67T |
| 12 | 113496197,113496196 | 3 | 0 | 0 | A67V |
| 12 | 113496233,113496234 | 3 | 0 | 0 | M79T |
| 12 | 113496208 | 3 | 0 | 0 | P71A |
| 12 | 113496248,113496249 | 2 | 0 | 1 | Q84H |
| 12 | 113496248,113496249 | 2 | 0 | 1 | Q84P |
| 12 | 113496248,113496249 | 2 | 0 | 1 | Q84R |
| 12 | 113496076 | 3 | 0 | 0 | V27M |
| 12 | 113496191 | 2 | 1 | 0 | V65G |
| 12 | 113496205,113496206 | 2 | 0 | 1 | V70A |
| 12 | 113496148 | 2 | 0 | 0 | V51M |
| 12 | 113496217,113496218 | 2 | 0 | 0 | I74T |
| 12 | 113496217,113496218 | 2 | 0 | 0 | I74V |
| 12 | 113496178 | 2 | 0 | 0 | V61F |
| 12 | 113496178 | 2 | 0 | 0 | V61I |
| 12 | 113496121 | 1 | 0 | 0 | A42P |
| nan | nan | 1 | 0 | 0 | CH45WD |
| nan | nan | 1 | 0 | 0 | DA55ET |
| nan | nan | 1 | 0 | 0 | EN49DY |
| nan | nan | 1 | 0 | 0 | H34_W37del |
| nan | nan | 0 | 0 | 1 | V44Lfs*5 |
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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