KLHL6 Hotspots
| Chromosome | Coordinate (hg19) | DLBCL | FL | BL | HGVSp |
|---|---|---|---|---|---|
| 3 | 183273248,183273249 | 25 | 2 | 2 | L65P |
| 3 | 183273248,183273249 | 25 | 2 | 2 | L65Q |
| 3 | 183273248,183273249 | 25 | 2 | 2 | L65V |
| 3 | 183273248,183273249 | 25 | 2 | 2 | L65del |
| 3 | 183273173,183273174 | 15 | 4 | 0 | L90F |
| 3 | 183273173,183273174 | 15 | 4 | 0 | L90V |
| 3 | 183273173,183273174 | 15 | 4 | 0 | L90P |
| 3 | 183273173,183273174 | 15 | 4 | 0 | L90Qfs*17 |
| 3 | 183273173,183273174 | 15 | 4 | 0 | L90R |
| 3 | 183273173,183273174 | 15 | 4 | 0 | L90S |
| 3 | 183273161,183273162 | 8 | 3 | 0 | S94N |
| 3 | 183273223,183273225,183273224 | 8 | 3 | 0 | D73E |
| 3 | 183273223,183273225,183273224 | 8 | 3 | 0 | D73N |
| 3 | 183273223,183273225,183273224 | 8 | 3 | 0 | D73H |
| 3 | 183273161,183273162 | 8 | 3 | 0 | S94G |
| 3 | 183273223,183273225,183273224 | 8 | 3 | 0 | D73A |
| 3 | 183273161,183273162 | 8 | 3 | 0 | S94C |
| 3 | 183273161,183273162 | 8 | 3 | 0 | S94I |
| 3 | 183273161,183273162 | 8 | 3 | 0 | S94T |
| 3 | 183273154,183273155,183273156 | 7 | 3 | 0 | Y96D |
| 3 | 183273154,183273155,183273156 | 7 | 3 | 0 | Y96F |
| 3 | 183273154,183273155,183273156 | 7 | 3 | 0 | Y96S |
| 3 | 183273154,183273155,183273156 | 7 | 3 | 0 | Y96* |
| 3 | 183273154,183273155,183273156 | 7 | 3 | 0 | Y96H |
| 3 | 183273152,183273153 | 6 | 1 | 0 | F97L |
| 3 | 183273193,183273194,183273195 | 5 | 2 | 0 | F83L |
| 3 | 183273193,183273194,183273195 | 5 | 2 | 0 | F83I |
| 3 | 183273193,183273194,183273195 | 5 | 2 | 0 | F83S |
| 3 | 183273193,183273194,183273195 | 5 | 2 | 0 | F83V |
| 3 | 183273152,183273153 | 6 | 1 | 0 | F97S |
| 3 | 183273231 | 5 | 0 | 0 | L71V |
| 3 | 183273269 | 3 | 1 | 0 | L58P |
| 3 | 183273164 | 4 | 0 | 0 | A93G |
| 3 | 183273164 | 4 | 0 | 0 | A93Qfs*14 |
| 3 | 183273164 | 4 | 0 | 0 | A93V |
| 3 | 183273164 | 4 | 0 | 0 | A93del |
| 3 | 183273170 | 3 | 0 | 0 | A91V |
| 3 | 183273201 | 3 | 0 | 0 | Q81* |
| 3 | 183273196,183273198 | 2 | 1 | 0 | E82D |
| 3 | 183273186,183273185 | 2 | 0 | 1 | H86Y |
| 3 | 183273187,183273188,183273189 | 3 | 0 | 0 | C85R |
| 3 | 183273187,183273188,183273189 | 3 | 0 | 0 | C85W |
| 3 | 183273187,183273188,183273189 | 3 | 0 | 0 | C85Y |
| 3 | 183273196,183273198 | 2 | 1 | 0 | E82Q |
| 3 | 183273186,183273185 | 2 | 0 | 1 | H86L |
| 3 | 183273176,183273177 | 1 | 2 | 0 | V89E |
| 3 | 183273176,183273177 | 1 | 2 | 0 | V89G |
| 3 | 183273176,183273177 | 1 | 2 | 0 | V89M |
| 3 | 183273206 | 2 | 0 | 0 | D79V |
| 3 | 183273203,183273204 | 1 | 1 | 0 | I80N |
| 3 | 183273203,183273204 | 1 | 1 | 0 | I80V |
| 3 | 183273237,183273235 | 2 | 0 | 0 | N69D |
| 3 | 183273237,183273235 | 2 | 0 | 0 | N69K |
| 3 | 183273209,183273210 | 2 | 0 | 0 | V78E |
| 3 | 183273209,183273210 | 2 | 0 | 0 | V78L |
| 3 | 183273211 | 1 | 0 | 0 | C77W |
| 3 | 183273158 | 1 | 0 | 0 | N95S |
| 3 | 183273192 | 1 | 0 | 0 | S84T |
| 3 | 183273179 | 1 | 0 | 0 | V88E |
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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