SOCS1 Hotspots

Chromosome Coordinate (hg19) DLBCL FL BL HGVSp
16 11348988,11348989 26 4 2 S116N
16 11348988,11348989 26 4 2 S116T
16 11348988,11348989 26 4 2 S116R
16 11348988,11348989 26 4 2 S116I
16 11348961,11348962 22 5 0 S125T
16 11348961,11348962 22 5 0 S125R
16 11348961,11348962 22 5 0 S125N
16 11348961,11348962 22 5 0 S125I
16 11348961,11348962 22 5 0 S125Rfs*125
16 11348949,11348950,11348951 14 3 0 H129Q
16 11348949,11348950,11348951 14 3 0 H129N
16 11348949,11348950,11348951 14 3 0 H129Y
16 11348949,11348950,11348951 14 3 0 H129L
16 11348949,11348950,11348951 14 3 0 H129P
16 11348971,11348972 11 4 0 G122R
16 11348971,11348972 11 4 0 G122*
16 11348971,11348972 11 4 0 G122A
16 11348943,11348944,11348945 11 2 0 Q131*
16 11348943,11348944,11348945 11 2 0 Q131H
16 11348943,11348944,11348945 11 2 0 Q131L
16 11348943,11348944,11348945 11 2 0 Q131P
16 11348943,11348944,11348945 11 2 0 Q131R
16 11348943,11348944,11348945 11 2 0 Q131Rfs*122
16 11349093,11349095,11349094 9 1 0 W81*
16 11349018,11349020,11349019 10 0 0 S106R
16 11349018,11349020,11349019 10 0 0 S106G
16 11349018,11349020,11349019 10 0 0 S106Ifs*5
16 11349018,11349020,11349019 10 0 0 S106N
16 11349018,11349020,11349019 10 0 0 S106Rfs*14
16 11349093,11349095,11349094 9 1 0 W81G
16 11349093,11349095,11349094 9 1 0 W81L
16 11349093,11349095,11349094 9 1 0 W81R
16 11349099,11349101 8 1 0 F79L
16 11349099,11349101 8 1 0 F79V
16 11349099,11349101 8 1 0 F79I
16 11349099,11349101 8 1 0 F79S
16 11348853,11348855 8 0 0 M161I
16 11348853,11348855 8 0 0 M161L
16 11349003,11349004 7 0 0 C111W
16 11349003,11349004 7 0 0 C111F
16 11349003,11349004 7 0 0 C111S
16 11349003,11349004 7 0 0 C111Y
16 11349006 5 1 0 N110K
16 11348920 5 1 0 G139V
16 11349040 4 2 0 G99D
16 11349037,11349038 6 0 0 T100I
16 11348977,11348978 6 0 0 A120G
16 11348977,11348978 6 0 0 A120V
16 11348920 5 1 0 G139D
16 11349040 4 2 0 G99A
16 11349037,11349038 6 0 0 T100S
16 11348977,11348978 6 0 0 A120T
16 11348977,11348978 6 0 0 A120_S121dup
16 11349037,11349038 6 0 0 T100P
16 11348932,11348933 4 1 0 F135C
16 11348956 5 0 0 R127H
16 11348923,11348924 3 2 0 D138G
16 11348923,11348924 3 2 0 D138H
16 11348959,11348960 5 0 0 I126T
16 11348923,11348924 3 2 0 D138A
16 11348932,11348933 4 1 0 F135L
16 11348959,11348960 5 0 0 I126F
16 11348959,11348960 5 0 0 I126L
16 11348959,11348960 5 0 0 I126Tfs*126
16 11348956 5 0 0 R127P
16 11349047 4 0 0 P97A
16 11349047 4 0 0 P97S
16 11349012 3 0 0 Q108H
16 11348981,11348980 3 0 0 M119V
16 11349011,11349010 2 1 0 R109W
16 11349028 3 0 0 V103dup
16 11348983,11348984 3 0 0 K118E
16 11348983,11348984 3 0 0 K118R
16 11348983,11348984 3 0 0 K118Sfs*136
16 11349032,11349031 3 0 0 L102Pfs*15
16 11349032,11349031 3 0 0 L102Q
16 11349032,11349031 3 0 0 L102V
16 11348981,11348980 3 0 0 M119K
16 11348968,11348969 3 0 0 P123L
16 11348968,11348969 3 0 0 P123S
16 11348968,11348969 3 0 0 P123Sfs*79
16 11349011,11349010 2 1 0 R109Q
16 11349028 3 0 0 V103G
16 11348930 0 2 0 H136Y
16 11348852 2 0 0 L162V
16 11349022 1 1 0 D105A
16 11349022 1 1 0 D105G
nan nan 2 0 0 E91Afs*24
nan nan 2 0 0 E91Gfs*22
16 11349035 1 1 0 F101I
16 11349035 1 1 0 F101L
16 11349001 1 1 0 F112S
16 11349001 1 1 0 F112Y
16 11348935,11348936 1 1 0 R134C
16 11348935,11348936 1 1 0 R134L
16 11348987 1 1 0 V117L
16 11348987 1 1 0 V117M
16 11348995 1 0 0 A114D
nan nan 1 0 0 A89_L93delinsV
nan nan 1 0 0 E96Rfs*19
16 11348998 1 0 0 F113S
16 11348948 0 1 0 F130L
16 11348938 1 0 0 G133A
nan nan 1 0 0 G88Cfs*25
16 11349026 1 0 0 R104C
16 11349017 1 0 0 R107G
nan nan 1 0 0 T124Afs*71
16 11348953 1 0 0 V128G
nan nan 1 0 0 V98Rfs*19

Citing

If you use the information or data from this site, please cite

Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.

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