Year Focus Methodology Novel genes Example gene Study
1992 DLBCL Sanger 1 BCL2 Tanaka et al. (1992)
1992 BL Sanger 1 MYC Johnston and Carroll (1992)
2001 DLBCL Sanger 4 PIM1 (pasqualucciHypermutationMultipleProtooncogenes2001a?)
2004 BL Sanger 1 TP53 Wilda et al. (2004)
2006 DLBCL Sanger 1 PRDM1 (pasqualucciInactivationPRDM1BLIMP12006a?)
2006 PMBL Sanger 2 SOCS1 (wenigerMutationsTumorSuppressor2006a?)
2007 DLBCL Sanger 1 FAS Scholl et al. (2007)
2008 DLBCL Sanger 1 NOTCH2 Trøen et al. (2008)
2008 DLBCL Sanger 1 CARD11 Lenz et al. (2008)
2009 DLBCL Sanger 1 TNFAIP3 (compagnoMutationsMultipleGenes2009a?)
2009 PMBL Sanger 1 STAT6 (ritzRecurrentMutationsSTAT62009a?)
2009 DLBCL Sanger 1 NFKBIA Lake et al. (2009)
2009 PMBL Sanger 1 TNFAIP3 (schmitzTNFAIP3A20Tumor2009a?)
2010 FL RNA-seq/WGS 1 EZH2 (morinSomaticMutationsAltering2010a?)
2010 FL Sanger 1 TNFRSF14 (cheungAcquiredTNFRSF14Mutations2010a?)
2011 DLBCL exome 2 EP300 (pasqualucciInactivatingMutationsAcetyltransferase2011a?)
2011 DLBCL RNA-seq/WGS 29 CD79B Morin et al. (2011)
2011 DLBCL exome 7 KLF2 Pasqualucci et al. (2011)
2011 MZL Sanger 5 TRAF3 (rossiAlterationBIRC3Multiple2011a?)
2011 DLBCL exome/Sanger 1 BRAF (tiacciBRAFMutationsHairycell2011a?)
2011 DLBCL Sanger 1 MYD88 (ngoOncogenicallyActiveMYD882011a?)
2012 BL exome 60 SLC29A2 Love et al. (2012)
2012 MZL exome 21 HIST1H2BK (rossiCodingGenomeSplenic2012c?)
2012 DLBCL exome 39 HIST1H2BC (lohrDiscoveryPrioritizationSomatic2012a?)
2012 DLBCL WGS 1 CXCR4 Khodabakhshi et al. (2012)
2012 BL RNA-seq 20 PDCD11 Schmitz et al. (2012)
2012 BL RNA-seq/WGS/exome 5 SMARCA4 (richterRecurrentMutationID32012a?)
2012 MZL Panel 2 MYD88 (yanBCRTLRSignaling2012a?)
2012 DLBCL Sanger 1 MIR142 (kwanhianMicroRNA142Mutated202012b?)
2012 PMBL Array/Sanger 2 MAP3K14 (ottoGeneticLesionsTRAF32012a?)
2012 MZL Array/Sanger 1 ATM Braggio et al. (2012)
2013 MZL exome 8 USH2A Parry et al. (2013)
2013 MCL WGS/exome 27 ABCA3 Beà et al. (2013)
2013 DLBCL WGS 38 P2RX5 Morin et al. (2013)
2013 DLBCL Sanger 1 EBF1 Bohle et al. (2013)
2013 DLBCL exome 16 FBXW7 Zhang et al. (2013)
2014 PMBL WGS/Sanger 1 PTPN1 (gunawardanaRecurrentSomaticMutations2014c?)
2014 MCL exome 28 SI Zhang et al. (2014)
2014 BL Sanger 3 ARHGEF1 (muppidiLossSignalingGa132014b?)
2015 FL Sanger 1 STAT6 (yildizActivatingSTAT6Mutations2015c?)
2015 PMBL exome 29 EBF1 (reichelFlowSortingExome2015a?)
2015 PMBL Sanger 1 CD58 (schneiderAlterationsCD58Gene2015a?)
2015 PMBL Sanger 1 CIITA (mottokGenomicAlterationsCIITA2015b?)
2015 BL RNA-seq 1 CCNF (abateDistinctViralMutational2015a?)
2015 DLBCL Sanger 1 MAP2K1 Shin et al. (2015)
2016 FL exome 1 MAP2K1 (louissaintPediatrictypeNodalFollicular2016a?)
2016 MZL exome 1 KLHL6 Ganapathi et al. (2016)
2016 MZL exome/panel 31 CDC42BPB (spinaGeneticsNodalMarginal2016b?)
2016 DLBCL exome 1 XPO1 Mareschal et al. (2016)
2016 PMBL Sanger 1 XPO1 (jardinRecurrentMutationsExportin2016a?)
2016 DLBCL exome 2 NFKBIZ Morin et al. (2016)
2016 FL WGS 3 ATP6V1B2 (okosunRecurrentMTORC1activatingRRAGC2016a?)
2016 MCL exome 1 CARD11 Wu et al. (2016)
2016 PMBL exome/Sanger 1 NFKBIE Mansouri et al. (2016)
2017 MZL panel 2 TNIP2 van den Brand et al. (2017)
2017 FL exome 22 HIST1H2AM (krysiakRecurrentSomaticMutations2017b?)
2017 MZL exome 28 ARHGEF17 Jallades et al. (2017)
2017 DLBCL exome 3 TET2 (albuquerqueEnhancingKnowledgeDiscovery2017a?)
2017 DLBCL exome 58 DCAF6 Reddy et al. (2017)
2018 PMBL exome 10 STAT5B (tiacciPervasiveMutationsJAKSTAT2018b?)
2018 DLBCL exome 19 DOCK1 (chapuyMolecularSubtypesDiffuse2018b?)
2018 PMBL Sanger 1 IL4R (viganoSomaticIL4RMutations2018b?)
2018 DLBCL exome 16 GSG2 (schmitzGeneticsPathogenesisDiffuse2018a?)
2018 DLBCL WGS 19 RFTN1 Arthur et al. (2018)
2019 BL RNA-seq/exome 47 LTB Panea et al. (2019)
2019 BL exome 1 KMT2C Zhou et al. (2019)
2019 PMBL exome 21 RGS1 (mottokIntegrativeGenomicAnalysis2019b?)
2019 BL WGS 13 BCL7A Grande et al. (2019)
2019 PMBL exome 7 RBM38 (wienandGenomicAnalysesFlowsorted2019b?)
2020 PMBL panel 10 KMT2D Desch et al. (2020)
2020 MCL WGS/exome 7 HNRNPH1 Pararajalingam et al. (2020)
2020 MCL WGS 5 TERT (nadeuGenomicEpigenomicInsights2020b?)
2020 FL panel 1 CTSS (barariaCathepsinAlterationsInduce2020c?)
2020 DLBCL exome/panel 1 MS4A1 Rushton et al. (2020)
2021 PMBL exome 14 RFTN1 (dunsCharacterizationDLBCLPMBL2021b?)
2021 PMBL exome 11 HIST1H1B (sarkozyMutationalLandscapeGray2021a?)
2021 DLBCL WGS 38 HLA-DQA1 (hubschmannMutationalMechanismsShaping2021b?)
2022 BL panel 25 NOA1 (burkhardtClinicalRelevanceMolecular2022b?)
2023 FL exome 20 CD70 (russler-germainMutationsAssociatedProgression2023b?)
2023 BL WGS 5 EBF1 Thomas et al. (2023)
2023 PMBL exome 7 OR13C2 Gomez et al. (2023)

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