Therapeutic targets
| Gene | Status | Entity | Therapy | Biomarkers |
|---|---|---|---|---|
| CD79B | FDA approved | DLBCL | polatuzumab vedotin | ABC gene expression signature |
| EZH2 | FDA approved | FL | tazemetostat | Mutation |
| XPO1 | FDA approved | DLBCL | selinexor | Not applicable |
| BCL2 | ongoing | DLBCL | venetoclax | Not applicable |
| BTK | ongoing | DLBCL | ibrutinib | ABC gene expression signature, MCD genetic subgroup |
References
Citing
If you use the information or data from this site, please cite
Krysta Coyle, Kostiantyn Dreval, Daniel Hodson and Ryan D. Morin. Audit of B-cell cancer genes. Blood Adv (2025) 9 (8): 2019–2031.
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