Summary of novel genes

Entity Tier 1 genes Tier 2 genes Tier 3 genes
MCL 11 16 0
--- config: sankey: showValues: true linkColor: target width: 600 height: 300 nodeAlignment: right prefix: '(' suffix: ' genes)' --- sankey-beta This study, New Tier 1, 11 New Tier 1, MCL Tier 1, 11 This study, New Tier 2, 16 New Tier 2, MCL Tier 2, 16 This study, New Tier 3, 0 New Tier 3, MCL Tier 3, 0 All other MCL studies, MCL Tier 1, 12 All other MCL studies, MCL Tier 2, 30 All other MCL studies, MCL Tier 3, 0

Novel genes reported in this study

Tier 1

New gene MCL tier
ATM 1
BIRC3 1
CCND1 1
KMT2D 1
MEF2B 1
NOTCH1 1
NOTCH2 1
NSD2 1
SP140 1
TLR2 1
TP53 1

Tier 2

New gene MCL tier
ABCA3 2
ABCC9 2
CHMP4C 2
CRYBG3 2
DCP1B 2
DLGAP2 2
DNAJC6 2
KCNC2 2
KIAA1671 2
LUZP4 2
PCSK2 2
PDLIM3 2
RGS4 2
SLC17A6 2
TNRC6B 2
TRPM6 2

Details

Beà, Sílvia, Rafael Valdés-Mas, Alba Navarro, Itziar Salaverria, David Martín-Garcia, Pedro Jares, Eva Giné, et al. 2013. “Landscape of Somatic Mutations and Clonal Evolution in Mantle Cell Lymphoma.” Proceedings of the National Academy of Sciences 110 (45): 18250–55. https://doi.org/10.1073/pnas.1314608110.