Summary of novel genes
| Entity | Tier 1 genes | Tier 2 genes | Tier 3 genes |
|---|---|---|---|
| MCL | 11 | 16 | 0 |
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sankey-beta
This study, New Tier 1, 11
New Tier 1, MCL Tier 1, 11
This study, New Tier 2, 16
New Tier 2, MCL Tier 2, 16
This study, New Tier 3, 0
New Tier 3, MCL Tier 3, 0
All other MCL studies, MCL Tier 1, 12
All other MCL studies, MCL Tier 2, 30
All other MCL studies, MCL Tier 3, 0
Novel genes reported in this study
Tier 1
| New gene | MCL tier |
|---|---|
| ATM | 1 |
| BIRC3 | 1 |
| CCND1 | 1 |
| KMT2D | 1 |
| MEF2B | 1 |
| NOTCH1 | 1 |
| NOTCH2 | 1 |
| NSD2 | 1 |
| SP140 | 1 |
| TLR2 | 1 |
| TP53 | 1 |
Tier 2
| New gene | MCL tier |
|---|---|
| ABCA3 | 2 |
| ABCC9 | 2 |
| CHMP4C | 2 |
| CRYBG3 | 2 |
| DCP1B | 2 |
| DLGAP2 | 2 |
| DNAJC6 | 2 |
| KCNC2 | 2 |
| KIAA1671 | 2 |
| LUZP4 | 2 |
| PCSK2 | 2 |
| PDLIM3 | 2 |
| RGS4 | 2 |
| SLC17A6 | 2 |
| TNRC6B | 2 |
| TRPM6 | 2 |
Details
Beà, Sílvia, Rafael Valdés-Mas, Alba Navarro, Itziar Salaverria, David
Martín-Garcia, Pedro Jares, Eva Giné, et al. 2013. “Landscape of
Somatic Mutations and Clonal Evolution in Mantle Cell Lymphoma.”
Proceedings of the National Academy of Sciences 110 (45):
18250–55. https://doi.org/10.1073/pnas.1314608110.


