Summary of novel genes

Entity Tier 1 genes Tier 2 genes Tier 3 genes
PMBL 6 15 0
--- config: sankey: showValues: true linkColor: target width: 600 height: 300 nodeAlignment: right prefix: '(' suffix: ' genes)' --- sankey-beta This study, New Tier 1, 6 New Tier 1, PMBL Tier 1, 6 This study, New Tier 2, 15 New Tier 2, PMBL Tier 2, 15 This study, New Tier 3, 0 New Tier 3, PMBL Tier 3, 0 All other PMBL studies, PMBL Tier 1, 40 All other PMBL studies, PMBL Tier 2, 97 All other PMBL studies, PMBL Tier 3, 0

Novel genes reported in this study

Tier 1

New gene PMBL tier
CISH 1
DDX3X 1
EZH2 1
IRF8 1
JAK1 1
MS4A1 1

Tier 2

New gene PMBL tier
CXCR5 2
EPHA7 2
GCSAM 2
HIST1H2BC 2
HIST1H4E 2
HIST1H4J 2
IL13RA1 2
IL1RAPL2 2
IRF2BP2 2
IRF4 2
JUNB 2
MAGEC2 2
NFKB2 2
RGS1 2
VMP1 2

Details

Mottok, Anja, Stacy S. Hung, Elizabeth A. Chavez, Bruce Woolcock, Adèle Telenius, Lauren C. Chong, Barbara Meissner, et al. 2019. “Integrative Genomic Analysis Identifies Key Pathogenic Mechanisms in Primary Mediastinal Large B-cell Lymphoma.” Blood 134 (10): 802–13. https://doi.org/10.1182/blood.2019001126.

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